The domain within your query sequence starts at position 417 and ends at position 491; the E-value for the 2yu2 domain shown below is 1e-17.

ATEVSTKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHVDD
DPTLAITGVPVVSWP

This is a PDB domain - please see the PDBSUM entry of 2yu2 for further annotation